Barcelona host Athletic Bilbao looking to reinstate their five point lead over Real Madrid at the top.
Real beat Levante 2-0 on Saturday to bring the gap between the arch-rivals down to two points.
Barca played their Champions League last-16 first leg on Wednesday, and it ended in disappointment as they conceded two late goals to go down 2-1 away to Arsenal.Despite that loss, which followed the surprise draw against Sporting, defender Dani Alves is staying calm, saying: "We're fine. There's no need for alarm bells. We have to be super-positive, there's still the second game to play."
The Catalans play host to fifth-placed Athletic, who saw their four-game winning streak ended on Monday night when they were beaten by Real Mallorca.
Athletic's defeat will have been a relief to fourth-placed Villarreal, who still boast a seven-point lead over the Basque side despite suffering surprise losses in their last two matches. The Yellow Submarine play rock-bottom Malaga.
Also on Sunday, Getafe host Racing Santander, Deportivo La Coruna go to Almeria and Sevilla meet Hercules. Osasuna, who on Monday sacked coach Jose Antonio Camacho and replaced him with Jose Luis Mendilibar, are at home to Espanyol.
On Monday night, Real Sociedad take on Mallorca.
